Publications

 

Books

 

1.      P.V.G.K. Sarma “Molecular Biology A Practical Manual” (2017) MJP publishers. ISBN No. 978-81-8094-340-9.

2.      Swathi Somisetty, P. Santhosh Kumar and P.V.G.K. Sarma (2017) Role of ANN Techniques in Detection of Breast Cancer. Lambert Academic publishing. ISBN No. 978-3-330-34470-9.

3.      Nanda Kumar Yellapu, Sarma PVGK and Bhaskar Matcha (2017) Structure and functional correlations of Human glucokinase, Lambert Academic publishing. ISBN: 978-3-659-63553-3.

4.      P.V.G.K. Sarma “A practical text book of Genetic Engineering in Bacteria” (2019) MJP publishers (Accepted).

Book Chapter Published

 

1.      Sarma PVGK and Sivakumar V (2010) “The Diagonsis of Autosomal Dominant Polycystic Kidney Disease”. Chapter written in the book Polycystic Kidney Disease, edited by K.V. Dakshinamurthy, ECAB clinical update Nepherology.  ELESEVIER publications.

2.      Sarma PVGK.and Sivakumar V (2010) “The Diagonsis of Autosomal Dominant Polycystic Kidney Disease”. Chapter written in the book Polycystic Kidney Disease, edited by K.V. Dakshinamurthy, ECAB clinical update Nepherology.  ELESEVIER publications.

3.      Kumar PS, Chandrasekhar C, Srikanth L, Sunitha MM, Sarma PVGK (2019). “In vitro differentiation and characterization of Human hematopoietic CD34+ stem cells into Erythrocytes”. Chapter written in the book Stem cells of Origins of cytokine interactions, edited by Prasad S Koka, Nova Medicine and Health, New York.

4.      Chandrasekhar C, Kumar PS, Kumar MS, Sarma PVGK (2019). “A Retrospective Study of JAK-2 Mutations, Endogenous Erythroid Colony Formation Assay in Absolute Erythrocytosis Patients in a Tertiary Care Centre, South India”. Chapter written in the book Stem cells of Origins of cytokine interactions, edited by Prasad S Koka, Nova Medicine and Health, New York.

5.      Kannan T, Sunitha MM, Srikanth L, Santhosh Kumar P, Chandrasekhar C, Sarma PVGK (2019). In vitro proliferation of human haematopoietic stem cells by Andrographis paniculata (Burm.f.) Nees extracts. Chapter written in the book Stem cells of Origins of cytokine interactions, edited by Prasad S Koka, Nova Medicine and Health, New York.

6.       Srikanth, L, Sarma PVGK (2019). Gold nanoparticles in the use of cancer therapy. . Chapter written in the book “Emerging Trends in Nanotechnology:Innovations, Health and Risks”, edited by S. Janardana Reddy (Accepted).

 

Papers presented in National/International conferences:  120

Gene/Protein sequences deposited in GenBank: 325. https://www.ncbi.nlm.nih.gov/

 Papers published

Bacterial genetics

1.      Sarma PVGK, Sarma PU, Murthy PS. Isolation, purification and characterization of intracellular calmodulin like protein (CALP) from Mycobacterium phlei. FEMS Microbiol Lett. 1998;1;159(1):27-34.

2.      Kumar A, Kumar S, Sarma, PVGK, Sharma AK. Differential Conformational Environment of Tryptophan in Epsilon Native Prototoxin and Active Toxin From Clostridium Perfringens Type D'. Journal of Biochemistry, Mol.Biol.& Biophys., 2002;6(2):147-150.

3.      Manjunath M, Sarma PVGK, Reddy OVS. In vitro Evaluation of antibacterial activity of Actiniopteris radiata (Sw.)Link. Journal of pharmacy and chemistry. 2008;2(2):112-118.

4.      Sarma PVGK, Hari Prasad O, Prasad UV, Manohar Reddy M, Kumar Swamy Reddy K, Subramanyam G. Purification and characterization of Human Intestinal alkaline phosphatase and its role in the colonization of Helicobacter pylori in the duodenum. Current Trends in Biotechnology and Pharmacy. 2009;3(4):390-396.

5.      Himakar Reddy K, Bala Nagi Reddy K, Sarma PVGK, Reddy OVS. In vitro Studies on Antimicrobial and Antioxidant Activities of Dillenia indica Seed Extract. Journal of Pure and Applied Microbiology. 2009;3(2):769-776.

6.      Hariprasad O, Gopinath VP, Navya A, Yugandhar VG, Sarma PVGK. Particulate vaccine for bacterial diseases. International Journal of Drug Discovery. 2010;2(2):17-19.

7.      Hari Prasad O, Nagarjuna V, Lakshmi Prasanna Ch, Vasu D, Yugandhar VG, Prasad UV, Srinivas Rao PVLN, Chaudhary A, Reddy OVS, Sarma PVGK. UV light Induces Transposition of blaZ gene resulting in high expression of β-lactamase in a clinical isolate of Staphylococcus aureus sensitive to amipicillin. Journal of pure and Applied Microbiology. 2010;4(2):609-616.

8.      Hari Prasad O, Navya A, Vasu D,  Chiranjeevi T, Bhaskar M, Sreedhar Babu KV, Sarma PVGK. Protective effects of Prosopis juliflora against Staphylococcus aureus induced hepatotoxicity in rats. Int J Pharm Biomed Res 2011;2(3):172-178.

9.      Hari Prasad O, Nanda Kumar Y, Reddy OV, Chaudhary A, Sarma PVGK. Cloning, expression, purification and characterization of UMP kinase from Staphylococcus aureus. Protein J. 2012;31(4):345-52. 

10.  Rathnakar Reddi KVN, Santhosh Kumar P, Venkateswara Prasad U, Yeswanth S, Swarupa V, Vasu D, Venkatesh K, Srikanth L, Nanda Kumar Y, Sarma PVGK. Isolation, purification and characterization of glucokinase from Staphylococcus aureus. Journal of pharmacy research 2013;6:205-209.

11.  Venkatesh K, Reiner G, Debral AK, Kirpan P, Reers M, Murthy PVVS, Swarupa V, Srikanth L, Sarma PVGK. pH Optimization and Production of High Potent Cellular Vaccine by Bordetella pertussis. International Journal of Biotechnology and Bioengineering Research 2012;3(1):17-25.

12.  Venkatesh K, Srikanth L, Swarupa V, Yeswanth S, Prasad UV, Vasu D, Vishnuvardhan GP, Srinivas P, Santhoshkumar P, Sowjenya G, Nandakumar Y, Chaudhary A, Sarma PVGK. Isolation, purification and characterization of pyruvate kinase from Staphylococcus aureus: a potential drug target. J Clin Sci Res 2012;1:76-82.

13.  Prasad UV, Vasu D, Kumar YN, Kumar PS, Yeswanth S, Swarupa V, Phaneendra BV, Chaudhary A, Sarma PVGK. Cloning, Expression and Characterization of NADP-Dependent Isocitrate Dehydrogenase from Staphylococcus aureus. Appl Biochem Biotechnol. 2013;169(3):862-9. 

14.  Lakshmi HP, Prasad UV, Yeswanth S, Swarupa V, Prasad OH, Narasu ML, Sarma PVGK. Molecular characterization of α-amylase from Staphylococcus aureus. Bioinformation. 2013;9(6):281-5.

15.  Swarupa V, Yeswanth S, Prasad UV, Vasu D, Venkatesh K, Srikanth L, Anitha P, Manasa C, Santhosh Kumar P, Sowjenya G, Nandakumar Y, Chaudhary A, Sarma PVGK. Characterization of succinate dehydrogenase flavoprotein from Staphylococcus aureus ATCC 12600. J Clin Sci Res 2013;2:81-87.

16.  Lakshmi HP, Yeswanth S, Prasad UV, Vasu D, Swarupa V, Kumar PS, Narasu ML, Sarma PVGK. Cloning, expression and characterization of glucokinase gene involved in the glucose-6-phosphate formation in Staphylococcus aureus. Bioinformation. 2013;9(4):169-173.

17.  Hari Prasad O, Nanda Kumar Y, Santhosh Kumar P, Reddy OVS, Chaudhary A, Sarma PVGK. Staphylococcus aureus TMPK and TK showing distinct structural differences with human TMPK and TK:A probable explanation in the pathogenesis. Journal of pharmacy research. 2013;7(1):1-7.

18.  Kishore KA, Hari Prasad O, Sudheer A, Mohan K, Vinay C, Chiranjeevi P, Bhaskar M, Sarma PVGK, Papa Rao A, Reddy R. Identification of predominant subgingival microbes in acute myocardial infarction patients of South Indian population. Journal of Indian college of cardiology, 2013;3:104-110.

19.  Yeswanth S, Kumar YN, Prasad UV, Swarupa V, Koteswara Rao V, Sarma PVGK. Cloning and Characterization of L-Lactate dehydrogenase gene of Staphylococcus aureus, Anaerobe 2013;24:43-48. 

20.  Yeswanth S, Lalith Kumar CH, Swarupa V, Prasad U.V,Vasu D, Nanda Kumar Y, Srikanth L, Venkatesh K, Sowjenya G, Santhosh kumar P, Kavya D, Chaudhary A, Sarma PVGK. Characterization of Inosine Monophosphate Dehydrogenase from Staphylococcus aureus ATCC12600 and its involvement in biofilm formation, J Clin Sci Res 2013;2:203-210.

21.  Swarupa V, Sundari R, Prasad UV, Yeswanth S, Sarma PVGK. Induced mutagenesis in Staphylococcus aureus ATCC 12600 resulting over expression of Streptomycin 3''-adenylyltransferase1, Journal of Pure and Applied Microbiology. 2013; 7(3) 2417-2422.

22.  Sarma PVGK, L.Srikanth, K. Venkatesh, P.S.N.Murthy, P.Usha Sarma. Isolation, purification and characterization of cardiolipin synthase from Mycobacterium phlei. Bioinformation.2013; 9(13): 690-695.

23.  Kumar PS, Kumar YN, Prasad UV , Yeswanth S, Swarupa V, Sowjenya G, Venkatesh K, Srikanth L, Rao VK, Sarma PVGK. In silico designing and molecular docking of a potent analog against Staphylococcus aureus porphobilinogen synthase. Journal of Pharmacy and Bioallied Sciences July-September 2014; 6 (3), 158-166

24.  Prasad UV, Swarupa V, Yeswanth S, Kumar PS, Kumar ES, Reddy KMK, Kumar YN, Jhansi Rani V, Chaudhary A, Sarma PVGK. Structural and Functional analysis of Staphylococcus aureus NADP-dependent IDH and its comparison with Bacterial and Human NADP dependent IDH. Bioinformation 2014;10(2):081-086.

25.  Kumar PS, Kumar YN, Prasad UV , Yeswanth S, Swarupa V, Venkatesh K, Srikanth L, Rao VK, Sarma PVGK. Comparative Structural and Functional Analysis of Staphylococcus aureus Glucokinase with other Bacterial Glucokinases. Indian Journal of Pharmaceutical Sciences 2014; 76(5):430-436.

26.  Swarupa V, Sundari RA, Prasad UV, Yeswanth S, Prasad OH, Sarma PVGK. Identification of methicillin resistant Staphylococcus aureus in raw cow milk through amplification of mecA. Journal of Pure and Applied Microbiology. 2014; 8(6) 4909-4915.

27.  Chiranjeevi T, Hari Prasad O, Prasad UV, Kumar AK, Praveen Chakravarthi V, Balaji Rao P, Sarma PVGK, Reddy N, Reddy R, Bhaskar M. Identification of Microbial Pathogens in Periodontal disease and Diabetic patients of South Indian Population. Bioinformation 2014;10(4): 241-244.

28.  Prasad UV, Vasu D, Yeswanth S, Swarupa V, Sunitha MM, Choudharry A, Sarma PVGK. Phosphorylation controls the functioning of Staphylococcus aureus Isocitrate dehydrogenase - favours biofilm formation. Journal of Enzyme Inhibition and Medicinal Chemistry. 2015;30(4):655-661.

29.  Vasu D, Sunitha MM, Srikanth L, Swarupa V, Prasad UV, Sireesha K, Yeswanth S, Kumar PS, Venkatesh K, Chaudhary A, Sarma PVGK. In Staphylococcus aureus the regulation of Pyruvate kinase activity by serine/threonine protein kinase favors biofilm formation. 3 Biotech. 2015; 5:505–512.

30.  Prasad UV, Vasu D, Gowtham RR,  Pradeep K, Swarupa V, Yeswanth S, Choudhary A, Sarma PVGK. Cloning, expression and characterization of NAD Kinase from Staphylococcus aureus involved in the formation of NADP (H)- a key molecule in the maintaining of redox status and biofilm formation. Advanced Biomedical Research. 2017;6:97.

31.  Swarupa V, Chaudhury A, Sarma PVGK. Effect of 4-methoxy 1-methyl 2-oxopyridine 3-carbamide on Staphylococcus aureus by inhibiting UDP-MurNAc-pentapeptide, peptidyl deformylase and uridine monophosphate kinase. J Appl Microbiol. 2017;122(3):663-675.

32.  Vasu D, Santhosh Kumar P, Venkateswara Prasad U, Swarupa V, Yeswanth S, Srikanth L, Sunitha MM,  Choudhary A, Sarma PVGK. In Staphylococcus aureus protein tyrosine kinase phosphorylation effects the functioning of glucokinase and biofilm formation. Iran Biomed J. 2017;21(2):94-105.

33.  Vasu D, Santhosh Kumar P, Kumar YN, Chakravarthi VP, Sarma PVGK. Structural and Functional Analysis of Serine/Threonine Protein Kinase of Staphylococcus aureus Exhibiting Variations with Other Bacterial PknB. J Anal Pharm Res. 2016;3(7):00081. DOI: 10.15406/japlr.2016.03.00081.

34.  Yeswanth S and Sarma PVGK. Proteins are the Major Players in the Formation of Staphylococcus aureus Biofilms. J Anal Pharm Res 2017; 4(2): 00097 (in press).

35.  Yeswanth S, Chaudhary A, Sarma PVGK. Quantitative expression analysis of SpA, FnbA and Rsp genes in Staphylococcus aureus - Actively associated in the formation of biofilms. Current Microbiology.2017; 74(12):1394–1403.

36.  Yeswanth S, Sekhar KC,  Chaudhary A, Sarma PVGK. Anti-microbial and Anti-biofilm activity of a novel Dibenzyl (benzo[d] thiazol-2-yl (hydroxy) methyl) phosphonate by inducing protease expression in Staphylococcus aureus. Med Chem Res.2017; DOI 10.1007/s00044-017-2102-8.

37.  Swarupa V, Chaudhury A, Krishna Sarma PVGK. Iron enhances the Peptidyl deformylase activity and biofilm formation in Staphylococcus aureus. Iron enhances the Peptidyl deformylase activity and biofilm formation in Staphylococcus aureus. 3 Biotech. 2018;8:32. doi: 10.1007/s13205-017-1050-9.

38.  Madhavi Latha P, Sharma KK, Mohan A, Kalawat U, Sarma PVGK. Role of microscopic agglutination test (mat) for the diagnosis of late /complicated leptospirosis. Eu.J.B.P.S. 2018; 5(4):455-459.

39.  Srikar A, Ramana BV, Mohan Alladi, Sarma PVGK, Gohain N, Prakash P, Chaudhary A. Comparison of three extraction methods for isolation of M. tuberculosis DNA for Genotypic studies and efficacy of heat killing after boiling. Int. J. of Sci. Res. 2019;8(6):59-61.

Fugal Genetics

40.  Sarma PVGK, Purkayastha S, Madan T, Sarma PU. Expression of an epitopic region of AspfI, an allergen/antigen/cytotoxin of Aspergillus fumigatus. Immunol Lett. 1999;70(3):151-5.

41.  Sarma PU, Sarma PVGK, Madan T. Challenges in prevention, diagnosis and therapy of emerging fungal diseases. Aspergillosis: A case study. Indian J Clin Biochem. 2000;15(Suppl 1):43-50.

42.  Nigam S, Sarma PVGK, Ghosh PC, Sarma PU. Characterization of Aspergillus fumigatus protein disulfide isomerase family gene. Gene. 2001;281(1-2):143-50.

43.  Reddy KH, Sharma PVGK, Reddy OV. A comparative in vitro study on antifungal and antioxidant activities of Nervilia aragoana and Atlantia monophylla. Pharm Biol. 2010;48(5):595-602.

44.  Reddy KH, Govender P, Reddy OVS, Sarma PVGK. Effect of hexane extract of Dillenia indica seed on the activity of secreted aspartyl proteinase of Candida albicans and its kinetic studies. Journal of Medicinal Plants Research. 2012;6(44),5599-5603.

45.  Reddy KH, Pillay K, Reddy OVS, Sarma PVGK, Govender P.  In vitro Antifungal, Antioxidant and Cytotoxic Activities of a Partially Purified Protein Fraction from Atlantia monophylla Linn (Rutaceae) Leaf. Tropical Journal of Pharmaceutical Research. 2015;14 (3):487-493.

46.  Reddy KH, Tharanath V, Nagi Reddy KB, Sarma PVGK, Reddy OVS. Studies on hepatoprotective effect of hexane extract of Dillenia indica against CCl 4 induced toxicity and its safety evaluation in wistar albino rats. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 2010;1(3):441–450.

Medical Genetics

47.  Naresh VVS, Reddy ALK, Sivaramakrishna G, Sarma PVGK, Vardhan RV, Siva Kumar V. Angiotensin converting enzyme gene polymorphism in type II diabetics with nephropathy. Indian Journal of Nephrology. 2009;19(4):145-148.

48.  Naresh VV, Reddy AL, Sivaramakrishna G, Sarma PVGK, Vardhan RV, Kumar VS. Angiotensin converting enzyme gene polymorphism in type 2 diabetics with nephropathy. Indian J Nephrol. 2010;20(2):119.

49.  Santhosh Kumar P, Srinivasa Rao V, Abdul K, Prasad UV, Nanda kumar Y, Sarma PVGK. Validation, quantitative and qualitative analysis of felodipine drug using HPLC. Journal of Pharmacy Research. 2012;5(4):1838-1840.

50.  Santhosh Kumar P, Jayanthi B, Abdul K, Prasad UV, Nanda Kumar Y, Sarma PVGK. A Validated High performance liquid chromatography (HPLC) Method for the Estimation of Cefuroxime axetil. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 2012;3(3): 223-228

51.   Kumar YN, Kumar PS, Sowjenya G, Rao VK, Yeswanth S, Prasad UV, Pradeepkiran JA, Sarma PVGK, Bhaskar M. Comparison and correlation of binding mode of ATP in the kinase domains of Hexokinase family. Bioinformation. 2012;8(12):543-547.

52.  Himabindu G, Rajasekhar D, Latheef K, Sarma PVGK, Vanajakshamma V, Chaudhury A, Bitla AR. Factor V Leiden mutation is not a predisposing factor for acute coronary syndromes. Indian Heart J. 2012;64(6):570-575.

53.  Kumar BS, Sarma PVGK, Reddy LK, Prajwal BM, Alladi Mohan, Kumar VS (2012). Mutation analysis of PKD1 gene in Indian population. Saudi J.Kidney.Dis. Transpl 2012;23(1), 143-147. 

54.  Kumar YN, Kalpana K, Swamy KV, Sarma PVGK, Bhaskar M. Molecular dynamics simulations of MODY 2 mutated Glucokinase structures revealed significant conformational variations explaining reasons for hyperglycemic condition. Int J Pharm Bio Sci, 2012;3(4):493–499.

55.  Srikanth L, Ramaiah J, Venkatesh K, Sriram P, Tejachandra G, Kannan T, Sarma PVGK. Differential Expression of ADH and ALDH2 can be a Diagnostic Marker in Gastroesophageal Cancer. Current Trends in Biotechnology and Pharmacy 2012;6(1):112-118.

56.  Swathi S, Rizwana S, Anjan Babu G, Santhosh Kumar P, Sarma PVGK. Classification of Neural network structures for Breast cancer diagnosis. International Journal of Computer Science and Communication, 2012;3(1):227-231.

57.  Swathi S, Rizwana S, Kumar PS, Sarma PVGK. Role of nutrition in prevention of breast cancer “a healthy diet is a magic bullet against cancer. Indian Journal of Women and Development.2012;Special volume:105-117.

58.  Nanda Kumar Y, Pradeep Kiran JA, Santhosh Kumar P, Yeswanth S, Kalpana K, Koteswara Rao V, Sarma PVGK, Bhaskar M. Molecular docking assessment of pyridone derivatives as glucokinase activators. J Clin Sci Res 2012;1:163-173.

59.  Yellapu NK, Kandlapalli K, Valasani KR, Sarma PVGK, Matcha B Structural Variations of Human Glucokinase Glu256Lys in MODY2 Condition Using Molecular Dynamics Study. Biotechnol Res Int. 2013;2013:264793.

60.  Kumar PS, Venkatesh K, Srikanth L, Sarma PVGK, Reddy AR, Subramanian S, Phaneendra BV. Novel three missense mutations observed in Von  Hippel-Lindau gene in a patient reported with renal cell carcinoma; Indian Journal of Human Genetics. 2013;19(3): 373-376.

61.  Yellapu N, Mahto MK, Valasani KR, Sarma PVGK, Matcha B. Mutations in exons 10 and 11 of human glucokinase result in conformational variations in the active site of the structure contributing to poor substrate binding - explains hyperglycemia in type 2 diabetic patients. J Biomol Struct Dyn. 2014;15:1-14.

62.  Kumar YN, Rao VK, Kumar PS, Sowjenya G, Sarma PVGK, Bhaskar M. Identification and analysis of novel R308K mutation in Glucokinase of type2 diabetic patient and its kinetic correlation. Biotechnology and Applied Biochemistry. 2014;61(5):572-581.

63.  Kumar YN, Navya A, Kalpana K, Ravendra Babu K, Jhansi Rani V, Hariprasad O, Nagaraju C, Sarma PVGK, Bhaskar M. Design, synthesis, in silico, and in vitro evaluation of novel pyrimidine phosphonates with cytotoxicity against breast cancer cells. Med Chem Res 2014; 23: 317-328.

64.  Kumar PS, Venkatesh K, Srikanth L, Prasad UV, Syama Sundar T, Ram Prasad Reddy A, Tyagi A, Radhika K, Sarma PVGK. Novel frame shift mutations (‘A’ deletion) observed in exon 9 ofWilms' tumor (WT1) gene in a patient reported with glomerulosclerosis. Gene 2014;546: 63–67.

65.  Kumar PS, Venkatesh K, Sowjenya G, Srikanth L, Sunitha MM, Prasad UV, Swarupa V, Yeswanth S, Naveen PSR, Sridhar A, Kumar VS, Sarma PVGK. Mutations in exons 3 and 7 resulting in truncated expression of human ATP6V1B1 gene showing structural variations contributing to poor substrate binding- causative reason for distal renal tubular acidosis with sensorineural deafness. Journal of Biomolecular Structure and Dynamics. 2015;33(10):2094-2103. 

66.  Naveen PSR, Srikanth L, Venkatesh K, Sarma PVGK, Sridhar N, Krishnakishore C, Sandeep Y, Manjusha Y, Kumar VS. Distal Renal Tubular Acidosis with Nerve Deafness Secondary to ATP6B1 Gene Mutation. Saudi J Kidney Dis Transpl.  2015; 26(1):119-121.

67.  Swathi S, Kumar PS, Sarma PVGK. Approach of Jordan Elman Neural Network to Diagnose Breast Cancer on Three Different Data Sets. International Journal of Advanced Research in Computer and Communication Engineering. 2015; 4(11): 321-325.

68.  Verma A, Jothibai S, Sarma PVGK, Nagaraj M, Srikant L, Vasavi B, Chandramouli P, Kalawat U. Prevalence of hepatitis C virus infection and its genotypes among the blood donors at Tirupati, Andhra Pradesh. J Clin Sci Res 2015;4:266-272.

69.  Kumar BS, Kumar PS, Sowgandhi N, Prajwal BM, Mohan A, Sarma KV, Sarma PVGK. Identification of novel mutations in CD2BP1 gene in clinically proven rheumatoid arthritis patients of south India, European Journal of Medical Genetics. 2016; 59: 404-412.

70.  Yellapu NK, Kilaru RB, Chamarthi N, Sarma PVGK, Matcha B. Structure based design, synthesis and biological evaluation of amino phosphonate derivatives as human glucokinase activators. Comput Biol Chem. 2017;68:118-130.

71.  Harsha EV, Rajashekar D, Vanaja V, Sarma PVGK, Sridhar K, Madhavi R, Kapil C. Evaluation of On-Clopidogrel platelet reactivity overtime, SYNTAX SCORE, genetic polymorphisms and their relationship to one year clinical outcomes in STEMI patients undergoing PCI. Minerva Cardioangiol. 2018;66(1):16-25.

72.  Madhavi R, Rajasekhar D, Sarma PVGK, Vanajakshamma V, Sowjenya G, Sreedhar K, Kapil C. Genetic Polymorphisms of ABCB1 Gene in patients having resistance to clopidogrel. World journal of cardiovascular diseases. 2017; 7:390-398.

73.  Chandrasekhar C, Kumar PS, Sugali RN, Kumar MS, Sarma PVGK. A study of parietal cell and intrinsic factor antibodies in B12 deficiency anaemias: a non-gastroscopic descriptive analysis in a university teaching hospital, India. Int.J.Sci.Res. 2018; 7(2):323-329.

74.  Babu PP, Kumar PS, Mohan A, Kumar BS, Sarma PVGK. Novel mutations in the exon 5, intron 2 and 3′ UTR regions of IL-12B gene were observed in clinically proven tuberculosis patients of south India. Cytokine. 2017; 99: 50–58.

75.  Prasad BCM, Chandra VVR, Sudarsan A, Kumar PS, Sarma PVGK. Clinical characteristics and NF1 gene mutation analysis of three successive generations in three different Indian families with neurofibromatosis type 1 and peripheral nerve sheath tumours. J Clin Neurosci. 2018; 53: 62–68.

76.  Sreedhar Naik K, Rajasekhar D, Vanajakshamma V, Kumar PS, Reddy DS, Sarma PVGK. Identification and analysis of novel mutations in NFKBIL1 gene in patients with myocardial infarction (mi) in south India. Int.J.Sci.Res. 2018;7(5): 28-31.

77.  Sowjenya G, Rajasekhar D , Velam Vanajakshamma V, PVLN Srinivasa Rao, PVGK Sarma. Polymorphism of Cytochrome P450 epoxygenase and its association with Endothelial Dysfunction in Patients with Coronary Artery Disease. Int. J. of Life Sciences, 2018; 6 (2):477-486.

78.  Dharaniprasad G, Samantaray A, Hanumantha Rao M, Chandra A, Sarma PVGK. Association of G472A allele of membrane bound catechol-O-methyltransferase gene with chronic post-sternotomy pain. General Thoracic and Cardiovascular Surgery. Gen Thorac Cardiovasc Surg. 2018 Aug 2. doi: 10.1007/s11748-018-0981-3.

79.  Praveena V, Kannan T, Bhargavi D, Sarma PVGK, Shilpa K, Kumar PS. Estimation of plasma Epidermal growth factor receptor (EGFR) mutation status and its correlation with tumor tissue EGFR mutation status in advanced non-small cell lung cancer patients. Indian Journal of Applied Research. 2018; 8(6):196-200.

80.  Latheef K, Rajasekhar D, Vanajakshamma V, Aparna BR, Chaudhury A, Sarma PVGK. Association of MTHFR, IL-6 and ICAM-1 gene Polymorphisms with Coronary Artery Disease in South-Indian Ethnic Subset: A Case-Control Study. J Cardiovasc Disease Res. 2018; 9(3):115-22.

81.  Chandrasekhar C, Kumar PS, Sarma PVGK. Novel mutations in the kinase domain of BCR-ABL gene cause imatinib resistance in chronic myeloid leukemia patients. Sci Rep. 2019 Feb 20;9(1):2412.

82.  Dharaniprasad G, Srikanth L, Ballweg R, PVGK Sarma, Indrakumar S, Samantaray A.

The journey of Physician Assistant’s in India: specialty areas to primary care. J Physician Assist Educ 2019;30(3):184–187.

83.  Dharaniprasad G, Srikanth L, Samantaray A, Hanumantha Rao M, Chandra A, Sarma PVGK. Novel Arg128Ala variant in Catechol-Omethyltransferase gene influence persistent pain. Clinical Genetics.  2019; Oct 24. doi: 10.1111/cge.13650.

Stem cells and Regenerative Medicine

84.  Sarma PVGK, Subramanyam G. In vitro cardiogenesis can be initiated in human CD34+ cells. Indian Heart J. 2008;60(2):95-100. 

85.  Venkatesh K, Srikanth L, Vengamma B, Chandrasekhar C, Sanjeevkumar A, Mouleshwara Prasad BC, Sarma PVGK. In vitro differentiation of cultured human CD34+ cells into astrocytes. Neurol India 2013;61:383-388.

86.  Venkatesh K, Srikanth L, Vengamma B, Chandrasekhar C, Mouleshwara Prasad BC, Sarma PVGK. In vitro transdifferentiation of Human cultured CD34+ stem cells into Oligodendrocyte precursors using Thyroid hormones. Neuroscience Letters. 2015; 588:36-41.

87.  Srikanth L, Sunitha MM, Venkatesh K, Kumar PS, Chandrasekhar C, Vengamma B, Sarma PVGK. Anaerobic Glycolysis and HIF1a Expression in Haematopoietic Stem Cells Explains Its Quiescence Nature. J Stem cells. 2015;10 (2):97-106.

88.  Srikanth L, Venkatesh K, Sunitha MM, Kumar PS, Chandrasekhar C, Vengamma B, Sarma PVGK. In vitro generation of Type II pneumocytes can be initiated in human CD34+ stem cells. Biotechnology Letters. 2016;38:237–242.

89.  Sunitha MM, Srikanth L, Santhosh Kumar P, Chandrasekhar C, Sarma PVGK.  In vitro differentiation potential of human hematopoietic CD34+cells towards pancreatic β cells.  Cell Biol Int. 2016;40(10):1084-1093.

90.  Srikanth L, Sunitha MM, Kumar PS, Chandrasekhar C, Vengamma B, Sarma PVGK. Gel based in vitro 3D model exploring the Osteocytic potentiality of human CD34+ stem cells. Molecular Biology Reports. 2016;43(11):1233-1242.

91.  Sunitha MM, Srikanth L, Kumar PS, Chandrasekhar C, Sarma PVGK. Role of STPK in maintaining the quiescent nature of human CD34 + stem cells. J Stem Cells. 2016;11(3):125-133.

92.  Kotakadi VS, Gaddam SA, Venkata SK, Sarma PV, Sai Gopal DV. Biofabrication and spectral characterization of silver nanoparticles and their cytotoxic studies on human CD34 +ve stem cells. 3 Biotech. 2016;6(2):216. doi: 10.1007/s13205-016-0532-5.

93.  Kumar PS, Chandrasekhar C, Srikanth L, Sunitha MM, Sarma PVGK. In vitro differentiation and characterization of Human hematopoietic CD34+ stem cells into Erythrocytes. J Stem Cells. 2017;12(2): 63-70.

94.   Chandrasekhar C, Kumar PS, Kumar MS, Sarma PVGK. A Retrospective Study of JAK-2 Mutations, Endogenous Erythroid Colony Formation Assay in Absolute Erythrocytosis Patients in a Tertiary Care Centre, South India. J Stem Cells. 2017;12(2):71-79.

95.  Sunitha MM, Srikanth L, Santhosh Kumar P, Chandrasekhar C, Sarma PVGK. Down regulation of PAX2 promotes in vitro differentiation of podocytes from human CD34+ cells. Cell Tissue Res. 2017; 370:477–488.

96.  Kannan T, Sunitha MM_, Srikanth L, Santhosh Kumar P, Chandrasekhar C, Sarma PVGK. In vitro proliferation of human haematopoietic stem cells by Andrographis paniculata (Burm.f.) Nees extracts. J Stem cells.2017; 12(4): 175-186.

97.  Kumar PS, Chandrasekhar C, Srikanth L, Sarma PVGK. In vitro large scale production of megakaryocytes to functional platelets from human hematopoietic stem cells. Biochem Biophys Res Commun. 2018; 505:168-175. doi: 10.1016/j.bbrc.2018.09.090.

98.  Kumar PS, Chandrasekhar C, Srikanth L, Sarma PVGK. Down-regulation of SOX17, GATA4 and FoxA2 promotes differentiation potential of hepatocytes from human hematopoietic stem cells. Tissue and Cell. 2019 (Accepted).

99.  Samundeshwari EL,  Srikanth L, Sireesha K, Surekha K, Chandrasekhar C, Rao MH, Vengamma B, Sarma PVGK. Identified cancer stem cells (CSCs) in ex- vivo cultured Acute Lymphoid Leukemia (B-ALL) cells. Journal of Stem cells. 2019; 14(2): (Accepted).