a) Completed: Research projects & Clinical drug trials:
1. INDO-US
Collaboration: “Memorandum of the understanding” was signed between
Department of Neurology, SVIMS. Prof.R.Ramamurthy, Dept.of Zoology,
S.V.University, Prof.Geeta Bali, Dept.of Zoology, Bangalore
University, Bangalore and John Savory, Ph.D., Mary M.Herman, MD of
University of Virginia, USA to colloborate with the research
projects on Neurotoxicity, Metal toxicity in biological systems and
Neuropathology, associated with toxins.
2.
Research collaboration
with Central Food Technological Research Institute (CFTRI) Mysore :
“Study of trace elements in Neuro-degenerative disorders in Serum
and CSF” – Colloborative study by Dr.K.S.Jagannatha Rao, Senior
Scientist, Dept.of Biochemistry and Nutrition, CFTRI, Mysore and
Dr.B.Vengamma, Dept.of Neurology, SVIMS.
3. Research
Member in “Rajiv Gandhi Water Mission Project on Trace Elemental
Toxicity in Kadiri Region of Andhra Pradesh” in collaboration with
CFTRI, Mysore.
4. Research
Collaboration with Jawaharlal Nehru for Advanced Scientific
Research, Bangalore on “National Collaborative Study on Genetics of
Juvenile myoclonic epilepsy” and attended the meeting on May 8th
1999 in the Department of Molecular Genetics at JNC for Advanced
Research, Bangalore.
5. ICMR
Project titled. “Anticonvulsant drug induced alteration in Calcium
and Vitamin D Metabolism” by Departments of Neurology &
Endocrinology, SVIMS.(Co investigator)
6. Drug
Trial entitled, “ A randomized, double-blind, placebo-controlled,
parallel group, multicenter study to evaluate the efficacy, safety
and tolerability of RWJ-333369 as adjunctive therapy in subjects
with partial onset seizures”
7. Protocol
: N01254 – “An International, randomized, double-blind, parallel
group, placebo-controlled, flexible dose study : Evaluation of the
safety and efficacy of brivaracetam in subjects ( > 16
to 70 years old) suffering from localization-related or generalized
epilepsy”
8. Drug
Trial entitled “A Randomized, Double-blind, Parallel-group,
Multicenter Study to Evaluate the Retention Rate, Efficacy,
Safety, and Tolerability of Carisbamate,Topiramate and Levetiracetam
as Adjunctive Therapy in Subjects with Partial Onset Seizures
(CARISEPY3007)
9. Project
titled “Efficacy of Revised National Tuberculosis Control Program [RNTCP]
treatment regimens in patients with various forms of neurological
tuberculosis: a prospective study” funded by RNTCP Govt.of India
10.
Protocol : N01199– “An
International, randomized, double-blind, parallel group,
placebo-controlled, flexible dose study : Evaluation of the
safety and efficacy of brivaracetam in subjects (> 16
to 70 years old) suffering from localization-related or generalized
epilepsy”
11.ICMR Project titled. “Status of Hypothalamic Pituitary axis in
patients with meningitis and Meningoencephalitis” by Departments of
Neurology & Endocrinology, SVIMS.(Co investigator)
12.
Drug Trial entitled
“An open, multicentric non-comparative study to assess, the effect
of phenobarbitone on cognition and behavior in pediatric patients
with generalized tonic-clonic seizures or partial seizures” - Phase
of IV clinical trial PROTOCOL NO.- GDL-PHL/09/08
13.
Poornima Sesha Sai Neelima Ch.”Assessment of Intracranial and
Extracranial carotid Vascular disease in patients presenting with
acute Ischemic stroke : a prospective study” (DM Neurology Thesis),
Sri Venkateswara Institute of Medical Sciences Tirupati, 2019
14.
Pynam Pranuthi ,”A Study of Prognostic significance of serum
Troponin I in patients with acute ischemic stroke” (DM Neurology
Thesis): Sri Venkateswara Institute of Medical Sciences Tirupati,
2019
15.
Rakesh Reddy Reddigari ,”A study on Association of CYP2C9
Polymorphisms with phenytoin toxicity” (DM Neurology Thesis): Sri
Venkateswara Institute of Medical Sciences Tirupati, 2019
b): Ongoing research projects & Clinical drug trials:
1. Dr.
Bhuma Vengamma: “Effect of Mobile phones on sleep, well-being and
Neuro-cognitive functioning”: a multicentric study Funding: Rs.
53,77,500/- Science and Engineering Research Board, Department
of Science and Technology, Government of India. Duration 3 years
(Co-principal investigator)
2. Madineni
K Usha “ A Study of Prognostic significance of increased Mean
platelet volume and platelet distribution width in patients with
Cerebral Venous Thrombosis” (DM Neurology Thesis): Sri Venkateswara
Institute of Medical Sciences, Tirupati, 2020
3. Tirupati
Kedar: “A study on Stroke Awareness and factors delaying
thrombolytic therapy in Acute Ischemic stroke patients at a tertiary
care hospital” (DM Neurology Thesis): Sri Venkateswara Institute of
Medical Sciences, Tirupati, 2020
4. Manideep
Malakala: Comparision of Frequency of motor and Non motor symptoms
in young onset versus late onset Parkinson’ disease” (DM Neurology
Thesis): Sri Venkateswara Institute of Medical Sciences, Tirupati,
2020
5. A.
Sunitha: “A study of Neuromyelitis optica spectrum disorders in
tertiary care centre in South India:
Sri Venkateswara Institute of Medical Sciences, Tirupati, 2021
6. G.
Sateesh: “A prospective study of clinical profile and outcome of
patients with acute ischemic stroke receiving intra venous
thrombolysis: Sri Venkateswara Institute of Medical Sciences,
Tirupati, 2021
7. K.
Srikanth: “A clinical study on the utility of nerve biopsy in
peripheral neuropathy”. Sri Venkateswara Institute of Medical
Sciences, Tirupati, 2021