Research Publications for the last one year

 

a.       Publications in indexed journals :

1.      Chiranjeevi Pasala, Sudheer Kumar Katari,Ravina Madhulitha Nalamolu, Aparna R. Bitla, Umamaheswari Amineni. Hierarchical-Clustering, Scaffold-Mining Exercises and Dynamics Simulations for Effectual Inhibitors Against Lipid-A Biosynthesis of Helicobacter pylori. Cellular and Molecular Bioengineering 2019.  https://doi.org/10.1007/s12195-019-00572-5.

2.      Manda P, Srinivasa Rao PVLN, Bitla AR, Vinapamula KS, Jeyaseelan L, Rajasekhar D, Vishnubhotla S.Study of contrast-induced oxidative stress in nondiabetic patients undergoing coronary angiography. Saudi J Kidney Dis Transpl. 2019;30(1):45-52.

3.      Sateesh R, Bitla AR, Budugu SR, Mutheeswariah Y, Narendra H, Phaneedra BV, et al. Oxidative stress in relation to obesity in breast cancer. Indian J Cancer 2019;56:41-4.

4.      Sasikala T, Bitla AR, Sachan A. Urinary brush border enzymes for early diagnosis of tubular dysfunction in patients with type 2 diabetes mellitus. Int J Res Med Sci 2019;7:2015-21.Geriki S, Bitla AR, SrinivasaRao PVLN, Hulikal N, Yootla M, Sachan A, Amancharla Yadagiri L, Asha T, Manickavasagam M, Kannan T, Kumari AP.  Association of single nucleotidepolymorphisms of adiponectin and laptin genes with breast cancer.  Mol Biol Rep. 2019. Doi: 10.1007/s11033-019-05070-5. [Epub ahead of print].

5.      B.Sandya Rani, M.M.Suchitra, PVLN.SrinivasaRao, V.Siva Kumar. Serum tumor markers in advanced stages of chronic kidney diseases.Saudi J Kidney Dis Transpl 2019;30(4):898-904.

6.      Pallavi M, Suchitra MM, AlokSachan, Lakshmi AY, SrinivasaRao PVLN. Role of adipokines, oxidative stress, and endotoxins in the pathogenesis of nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus.Int J Res Med Sci. 2019 ;7(5):1644-52.

7.      Narasimha S, Devi NH, Sachan A, Kumar VS. Atherogenic ratios and serum lipid levels in patients with end-stage renal disease on continuous ambulatory peritoneal dialysis. J NTR Univ Health Sci 2019;8:89-94.

8.      Anjani A, Harini Devi N, Nagaraj RD, Kumar VS. Burnt-out diabetes in diabetic nephropathy patients on maintenance haemodialysis. J Clin Sci Res 2019;8:7-10.

9.      Shaik Khaja Shanawaz Basha, T. Mahendra Reddy, Dudekula Shakir, Siddham Siva Prasad,R. Jayaraman, Harini Devi. N,  B. Shivanandh, Siva Kumar. V ^. PILL BURDEN, SLEEP QUALITY, ANXIETY, DEPRESSION IN PATIENTS WITH DIABETIC AND NON - DIABETIC CHRONIC KIDNEY DISEASE. Journal of Biomedical and Pharmaceutical Research. 2019;9:60-67.

10.  Kiranmayi VS, Bhargav KM. Brown adipose tissue in adult humans: A mini review. J Clin Sci Res 2019;8:24-8.

11.  Gowthami P, Kiranmayi VS, Rani BS, Suresh V, Vijayalakshmi Devi B. Study of serum adiponectin levels in women with polycystic ovary syndrome. Indian J ObstetGynecol Res 2019;6:288-92.

12.  Geriki S, Bitla AR, SrinivasaRao PVLN, Hulikal N, Yootla M, Sachan A, Amancharla Yadagiri L, Asha T, Manickavasagam M, Kannan T, Kumari AP. Association of single nucleotide polymorphisms of adiponectin and leptin genes with breast cancer. Mol Biol Rep. 2019. doi: 10.1007/s11033-019-05070-5. [Epub ahead of print]

Research work :

a)  Thesis work :

 i) Thesis submitted :

i)                    Dr Keerthi Tej Mitta.  Effect of Rosuvartatin on oxidative stress in patients with type 2 diabetes mellitus (MD Biochemistry).  Tirupati: Sri Venkateswara Institute of Medical Sciences; 2018; Guide: Dr.Aparna R.Bitla; Co-guides: Dr.Alok Sachan, Dr PVLN Srinivasa Rao

ii)                  Mr. Pullaiah P.  Effect of vitamin D supplementation on oxidative stress and inflammation in  patients with type 2 diabetes mellitus (PhD thesis). Tirupati: Sri Venkateswara Institute of Medical Sciences; 2018; Guide: Dr.M.M.Suchitra; Co-guides: Dr.Aparna R.Bitla, Dr.Alok Sachan

iii)                Mrs. Sasikala T.  Oxidative stress and inflammation in type 2 diabetes mellitus patients with subclinical atherosclerosis (Phd thesis). Tirupati: Sri Venkateswara Institute of Medical Sciences; 2018; Guide: Dr.M.M.Suchitra; Co-guides: Dr.Aparna R.Bitla, Dr.S.Sarala, Dr.V.Suresh.

iv)                Naresh S.  Study of anti-atherogenic effects of rosuvastatin in patients with type 2 diabetes mellitus (PhD Thesis – Biochemistry). Tirupati: Sri Venkateswara Institute of Medical Sciences; 2018; Guide: Dr Aparna R.Bitla. ; Co-guides:   Dr. Alok Sachan, Dr A.Y. Lakshmi.   

v)                  Ms. Sandya.  Association Of Bone Isoform Of Alkaline Phosphatase With Glycaemic Status In Patients With Type 2 Diabetes Mellitus. (Msc – Biochemistry).  Tirupati: Sri Venkateswara Institute of Medical Sciences; 2018; Guide: Dr. N. Harini Devi ; Co-guides:  Dr V. Suresh

 

vi)                Ms. E.Sukanya.  To Study The Association Of Salivary Urea With Oral Hygiene Index In Pre Dialysis Patients With Chronic Kidney Disease. (Msc – Biochemistry). Tirupati: Sri Venkateswara Institute of Medical Sciences; 2018; Guide: Dr. N. Harini Devi ; Co-guides:   Dr V. Siva Kumar, Dr Madhu Babu.

 

vii)              Ms. R.D.Priya.  To Study The Levels Of Urinary N-Acetylglucosaminidase In Patients With Type 1 Diabetes Mellitus. (MSc – Biochemistry). Tirupati: Sri Venkateswara Institute of Medical Sciences; 2018; Guide: Dr. N. Harini Devi ; Co-guides:   Dr. Alok Sachan.

Thesis work carried out in collaboration with other departments :

i)                    Thesis submitted - collaboration with other departments :

1.                  Pasala Chiranjeevi (ICMR-JRF) titled ‘Computer aided approach to identify drug targets, vaccine candidates and potent lead molecules against gastrointestinal pathogen Helicobacter pylori  (Co-guide) (PhD-Bioinformatics). Dr Aparna R Bitla

2.                  Katari Sudheer Kumar (DBT-JRF) titled ‘In-silico trials to identify potent inhibitors against matrix metalloproteinases in breast cancer  (Co-guide) (PhD-Bioinformatics). Dr Aparna R Bitla

3.                  Dr.A.Sunnesh Reddy.  To study the risk factor profile for thrombophilia in patients of ESRD on maintenance hemodialysis with failed AV fistulas (DM – Nephrology Thesis).  Tirupati: Sri Venkateswara Institute of Medical Sciences; 2019; Guide:  Dr. Ram;  Co-guides: Dr. V. Siva kumar, Dr. PVGK Sarma,  K.V. Sreedhar Babu, Dr. N. Harini Devi.

 

4.                  Dr.N.Sai Sameera.  A study of markers of oxidative stress, inflammation and endothelial dysfunction in diabetic and non-diabetic chronic kidney disease patients on peritoneal dialysis”(DM – Nephrology Thesis). Tirupati: Sri Venkateswara Institute of Medical Sciences; 2019; Guide: Dr. Ram; Co-guides:  Dr. V. Siva Kumar, Dr. A.Y. Lakshmi; Dr. N. Harini Devi;.

 

5.                  Dr. Ganesh.  A Study of Microalbuminuria In Sepsis With Reference To Acute Physiology And Chronic Health Evaluation II (APACHE II) Score In Patients Admitted To A Medical Intensive Care Unit (MICU) (MD – General medicine). Tirupati: Sri Venkateswara Institute of Medical Sciences; 2019; Guide:  Dr. T. Katyasmal; Co-guides: Dr. N. Harini Devi;  Dr. K.V.S. Sarma

 

6.                  Dr.Navakiran Reddy.  Comparison Of Performance Of SOFA And q SOFA Scoring System At The Time Of Admission In Critically Ill patients Who Requires Intubation In Emergency Department. (MD-Emergency Department). Tirupati: Sri Venkateswara Institute of Medical Sciences; 2019; Co-guide: Dr. N. Harini Devi.

 

7.                  Dr.Vinayakyerra. Clinical Profile Of Hypertensive patients Presenting To Emergency Department. (MD-Emergency Department). Tirupati: Sri Venkateswara Institute of Medical Sciences; 2019; Co-guide: Dr. N. Harini Devi.

8.                  Sowjanya J. Clinical features precipitating factors biochemical profile and outcome in relation to Inhospital care of Diabetic ketoacidosis: A prospective study (MD Emergency Medicine Thesis). Dr Kiranmayi VS

9.                  B Manoj. Evaluation of renal function after percutaneous nephrostomy or DJ stenting in calculus upper tract obstruction with renal failure (M.Ch Urology Thesis). Dr Kiranmayi VS

10.              Raghavendra K. Prevalence of Autonomic neuropathy in patients with type 2 Diabetes mellitus with special reference to Cardiac Autonomic neuropathy (DM Endocrinology Thesis). Dr Kiranmayi VS

11.              Mani Deepthi D. Effects of adequate treatment of Hyperthyroidism on glycated hemoglobin levels in non diabetic subjects with Hyperthyroidism (DM Endocrinology Thesis). Dr Kiranmayi VS

12.              Harshavardhan Reddy G. Etiology, clinical profile and outcome in patients with hyponatremia admitted to medical intensive care unit (MICU): A prospective study (MD Medicine Thesis). Dr Kiranmayi VS

13.              Devika Reddy Vakkakula.  A study of prevalence and determinants of thyroid dysfunction in patients with type 2 diabetes mellitus in a tertiary care hospital (MD Medicine Thesis). Dr Kiranmayi VS

ii) Ongoing Thesis work :

i)                    Dr P. Jyothsna.  Glycated albumin and glycated hemoglobin levels in type 2 diabetes mellitus patients with iron deficiency aneria (MD Biochemistry).  Tirupati: Sri Venkateswara Institute of Medical Sciences; 2018; Guide: M.M. Suchitra; Co-guides: Dr. Alok Sachan, Dr. N.Rukmangadha, Dr. M.Kusuma kumari.

iii) Thesis ongoing - collaboration with other departments:

1.      Dr Aparna R Bitla Co-guide for the thesis of Ms. Nalamolu Ravina Madhulitha working on "In silico identification of potential drug targets, vaccine candidates and inhibitor design against Mycobacterium tuberculosis "(PhD-Bioinformatics).

2.      Dr Aparna R Bitla Co-guide for thesis of Dr K.Naveen Kumar titled “A study of markers of oxidative stress, inflammation, endothelial dysfunction and ischemia in diabetic and non- diabetic chronic kidney disease patients not on dialysis”. (DM Nephrology)

3.      Dr Aparna R Bitla Co-guide for thesis of Dr. Maria Bethsaida Manual titled “Correlates of atherosclerotic vascular disease in stable postrenal trasplant patients ” . (DM Nephrology)

4.      Dr Aparna R Bitla Co-guide for thesis of Dr. Alekhya titled “ A study on markers of inflammation, and oxidative stress in patients with ESRD with peritonitis on peritoneal dialysis”. (DM Nephrology)

5.      Dr.M.M.Suchitra Co-guide MCh Urology: To study the outcome of renal failure in patients of chronic kidney disease following per cutaneous nephrolithotomy for symptomatic renal calculus disease

6.      Dr.M.M.Suchitra Co-guide MD Medicine – Dr.P.Seelabanu. A study of correlation of serum uric acid levels with glycosylated hemoglobin levels and fasting blood sugar levels in patients with type 2 diabetes mellitus

7.      Dr.M.M.Suchitra Co-guide MD Transfusion medicine. Dr.Keerti. Serological characterization of direct antiglobulin test positive autoimmune hemolytic anemia in a tertiary care teaching hospital in Tirupati.

8.      Dr.M.M.Suchitra Co-guide MD Medicine –Dr.Sairam. Status of serum electrolytes in patients before and after receiving platinum based chemotherapy.

9.      Dr Kiranmayi VS Co-guide Sandeep Ganta. Effect of frequent blood glucose monitoring on glycemic control in type 1 diabetes (DM Endocrinology Thesis).

10.   Dr Kiranmayi VS Co-guide Avinash Patil. Body composition and mediators of energy homeostasis in hyperthyroidism (DM Endocrinology Thesis).

11.  Dr Kiranmayi VS Co-guide Raja Amarendra Muthina.  Gonadal function and body composition in adult men with non diabetic chronic kidney disease (predialysis) (DM Nephrology Thesis).

12.  Dr. M. Kusuma Kumari Co-guide for thesis of Dr. Maria Bethsaida Manual titled “Correlates of atherosclerotic vascular disease in stable postrenal trasplant patients ” . (DM Nephrology).